Protein BioSolutions

Opti-Matrix Maker — Custom Crystallization Optimization Screens

For crystallographers, the task of optimizing after getting an initial hit has traditionally been tedious and prone to errors. Now the Opti-Matrix Maker™ lets you create a custom optimization screen right in your lab. No more calculating, measuring, or pipetting. Use your own stock solutions to create a precise, accurate matrix with up to 96 optimization formulations.

  • Mix up to 10 unique stock solutions, plus water
  • Choose a range of stocks. Compatible with organic, viscous, and varied pH solutions
  • Dispense into 96 blocks and well plates
  • Customize your matrices using intuitive, touchscreen controls
Opti-Matrix Maker instrument
EZ-Screen Composer software interface

Design a custom optimization screen using EZ-Screen Composer. EZ-Screen Composer is pre-loaded with screens from a number of different vendors. The software automatically designs an optimization screen around the conditions in the well that produced the hit. Adjust the chemicals, pH levels, and concentrations. Then export the data to the Opti-Matrix Maker for production.

Streamline the Design of Optimization Screens

When you get a hit in a crystallization screen, it's time to optimize. Add to generate the conditions and paste the various chemicals is a labor-intensive and error-prone process. The Opti-Matrix Maker takes the work out of designing and generating optimization screens. Generate the screen conditions with a few clicks of the mouse, then let the desktop instrument automatically dispense the chemicals into 96 blocks or well plates. The Opti-Matrix Maker can give you an accurate, next optimization screen minutes after you find your original crystal hit.

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