Protein Maker — Parallel Protein Purification Workstation
Accelerate your research on protein function with parallel purification. The Protein Maker workstation makes high-throughput protein purification chromatography simple by allowing you to run 24 columns, 50 mL or larger, in parallel, and process 8x samples unattended. Protein Maker's flexible design allows you to customize sample and column system to achieve a variety of tasks.
- Produce dozens of purified antibodies in a single day
- Evaluate gene expression levels
- Analyze functions of different enzymes or clones
- Determine the best protein or enzyme purification method for scaling up
- Screen constructs for protein structure studies
The new Protein Maker i-Software has a simulation mode that lets researchers create, test, edit, and archive new protein purification methods. In addition, the software includes modules for collecting and monitoring AI data, and gives scientists the ability to pause processes whenever they want.
Of course, the software also provides full control over the instrument's syringe pumps, valves, and robot XYZ gantry. Protein Maker i-S easily allows the user to adapt the instrument to their unique needs.
Parallel Protein Purification
- Load small (sub-mL) or large (4 L) volumes of each sample (up to 4 at a time)
- Load and customize purification method with simple but flexible software
- Fully automated purification set up and walks away, even run overnight
- Run 2 chromatography columns (0–20 mL or larger) in parallel
- Capable of running multi-column purification methods
- Track real-time results with our 6-channel UV Monitor at 254nm, 270nm or both
Applications
- Antibody purification from 5 mL or larger starting volume
- Bead-free purification scale-up through parallelization
- Multi-construct design for structural biology
- Lysis buffer scouting
Operational Modes
- Purification: 24 different protein samples, one type of chromatographic resin
- Scouting: 24 different chromatographic resins, one proven sample
- Multi-step: Automated, multi-column chromatography for up to 12 channels in parallel
Powerful, Flexible, Fast
Protein Maker 6i's flexible design lets you perform wide-ranging proteomics projects, or focus on a single gene product. It's easy to customize your sample size and purification method for high throughput production of pure protein for anything from antibody production to X-ray crystallography.
The Protein Maker 6 Workstation is a workhorse that makes higher throughput purification simple and efficient at an affordable price. Purify 6 samples in parallel through 6 separate columns.
Protein Maker 6i is simple, yet flexible design enables custom approaches to parallel purification on a preparative scale.
- Analyze functions of different subtypes, clones, antibodies
- Determine the best protein or method for scale-up
- Evaluate gene expression levels
- Produce hundreds to hundreds of purified samples in a week
- Screen constructs for protein structure studies
- Track all samples with independent UV traces
Links and Documentation
- › Protein Maker Brochure
- › Protein Maker Details and Specifications
- › Peer-reviewed paper on Lysis Scouting in Non-Crystallography
- › Therapeutic Proteins: Opportunities and Challenges in Early Stage Therapeutic Research and Development
- › Application of the Protein Maker as a platform purification system for therapeutic antibody research and development
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