The micro capillary Protein Crystallization System™, also known as the Plug Maker™, is a cutting-edge protein crystallization workstation designed to help you obtain crystals using as little as 1 nL of protein per experiment. This system allows for high-throughput, batch-type crystallization within microfluidic CrystalCards™, making it easy to screen Crystal conditions or study X-ray diffraction.
With the ability to screen, optimize, and produce diffraction-ready crystals, you can generate up to 600 individual experiments per CrystalCard using only about 1 µL of protein. Each CrystalCard can be used with up to 24 different conditions at varying concentrations, significantly increasing your chances of obtaining high-quality crystals.
Grow crystals in durable, x-ray transmissive microfluidic CrystalCards. Visualize crystallization sweet spots, transport crystals, or store them for months in these innovative cards. Easily remove crystals for traditional cryoprotection and x-ray diffraction studies. Alternatively, you can test crystals for x-ray diffraction inside the microfluidic CrystalCards using a simple goniometer adapter. Enhance your protein crystallization system with our Plug Maker to streamline the process further. with our Plug Maker to streamline your workflow.

These images showcase actual crystals that were grown inside microfluidic CrystalCards, along with the corresponding X-ray locations that emerged from our advanced protein crystallization system and Plug Maker.

Each micro-holder CrystalCard combines protein, precipitant, and buffer to screen protein crystallization conditions, and facilitates both high-throughput crystallization experiments, protein purification systems, and gradient screening ligand screening, crystallization experiments, and small-molecule screening gradient screening from our crystallization kits using the Plug Maker.
The Plug Maker enables the use of microfluidic CrystalCards in a plug-based nano-volume protein crystallization system, optimizing the growth of protein crystals. This system also facilitates the storage and storage of infectious disease protein targets.